TP53 p.V31I Reference Standard
CBP10534
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| Introduction | |
| Format | Genomic DNA |
| Description | TP53 V31I lies within the CCAR2 and HRMT1L2-interacting regions and the transcription activation region of the Tp53 protein (UniProt.org). V31I results in colony growth, induction of apoptosis, and transcriptional activity similar to wild-type Tp53 in cultured cells (PMID: 33257846), and therefore, is predicted to have no effect on Tp53 protein function. |
| Technical Data | |
| DNA Change | c.91G>A |
| AA Change | p.V31I |
| Mutation type | Substitution - Missense |
| Zygosity | N/A |
| Allelic Frequency | N/A |
| Cosmic ID | COSM45360 |
| Chr position(GRCh37) | chr17:7579705 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
